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On their way to a weekend concert Todd Remington and his college friends make a horrible mistake when they pick up a mysterious hitchhiker named Annabella. They soon realize there is something strange about their new passenger. With her flawless beauty that seduces men and women alike, she also knows things that are impossible to know. After their car breaks down, Annabella lures them to Blood River, a town not found on any map, where the townspeople live in fear and no one dares walk the streets at night. As the group beds down at the local boarding house an unspeakable horror awakens beneath the floorboards, and evil creatures ravenous for blood emerge seeking new prey