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Transformed into a giant after being hit by a meteor, Susan (voiced by Reese Witherspoon) is taken to a secret government prison that houses a group of bizarre creatures. But when an evil alien (Rainn Wilson) launches an attack on Earth, Susan and her fellow monsters--the gelatinous B.O.B. (Seth Rogen), Dr. Cockroach (Hugh Laurie), and the Missing Link (Will Arnett)--are the only ones who can save the planet. Paul Rudd, Amy Poehler also supply voices for this computer-animated sci-fi tale. 94 min. Widescreen; Soundtracks: English Dolby TrueHD 5.1, French Dolby Digital 5.1, Spanish Dolby Digital 5.1; Subtitles: English (SDH), French, Spanish; audio commentary; featurettes; deleted scenes; trivia; bonus short "B.O.B.'s Big Break" (2009); more.